TNF Receptor-1 (TNF-R1) Ubiquitous Scaffolding and Signaling Protein Interacts with TNF-R1 and TRAF2 via an N-Terminal Docking Interface
نویسندگان
چکیده
منابع مشابه
TNF-R1 signaling: a beautiful pathway.
Tumor necrosis factor (TNF) is a major mediator of apoptosis as well as inflammation and immunity, and it has been implicated in the pathogenesis of a wide spectrum of human diseases, including sepsis, diabetes, cancer, osteoporosis, multiple sclerosis, rheumatoid arthritis, and inflammatory bowel diseases. The interaction of TNF with TNF receptor-1 (TNF-R1) activates several signal transductio...
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ژورنال
عنوان ژورنال: Biochemistry
سال: 2010
ISSN: 0006-2960,1520-4995
DOI: 10.1021/bi100726n